New Research Findings — and Potential New Avenues for Drug Discovery — in Type 2 Diabetes

Many important basic discoveries about human biology have been made using “model organisms” — more primitive species with biological processes that have been carried down through evolution to humans. Recently, researchers at Vanderbilt University and the University of Michigan identified… Read »

Helping to Bring Precision Medicine to Community Oncology Practices

The use of precision medicine and targeted therapies in the treatment of cancer is quickly increasing. However, implementing such approaches in the community, where most patients are seen, often remains a challenge. Clinicians struggle to identify which molecular diagnostic tests… Read »

New Treatment Options for Hemoglobin-Based Blood Disorders

  Sickle cell disease is a group of inherited disorders that affects hemoglobin, the oxygen-carrying protein in red blood cells (RBCs), and causes these cells to distort in shape at low oxygen levels. This condition affects 1 in 500… Read »

New Treatments for Alzheimer’s Disease? Maybe.

The Alzheimer’s Association estimates that nearly six million Americans are living with the disease, a number that is expected to rise to 14 million by 2050. Marketed drugs such as memantine and donepezil modestly slow memory loss in some… Read »

Nobel Prize in Medicine Goes to Oxygen-Sensing Research

Breakthroughs in basic research have been key to creating new therapeutic paradigms. In October, the 2019 Nobel Prize in Physiology or Medicine was awarded jointly to William G. Kaelin Jr., Sir Peter J. Ratcliffe, and Gregg L. Semenza, for their… Read »

Digital Solutions to Drug Adherence

Non-adherence to medications, whether due to missed doses, drugs taken at the wrong time, or not taken at all, is a huge issue in healthcare, and can mean worse outcomes for patients. This has an economic impact on healthcare systems… Read »

The Changing Landscape for Pharma and Physician Interactions

A 2019 ePharma study from Decision Resources Group (DRG) found that an increasing number of physicians are searching for drug and treatment information on their own, rather than relying on meetings with pharmaceutical sales reps.   According to the report,… Read »

The SMA Market: Assessing the Unknowns

The FDA approvals of Biogen’s Spinraza (nusinersen) and Novartis’ gene therapy for spinal muscular atrophy (SMA), Zolgensma, were landmark events that brought to market the first disease-modifying therapies for this often devastating, genetic neuromuscular disease. They also form the basis… Read »

New Risk-Based Oversight of Software as a Medical Device

Digital initiatives and artificial intelligence/machine learning are rapidly becoming central elements of health care. In particular, new tools, apps and devices are fulfilling a variety of needs related to clinical decision support (CDS) that can range from simple tools for… Read »

First Peanut Allergy Immunotherapeutic Recommended for FDA Approval

Peanut allergy is one of the most common food allergies, affecting as many as 1 in 13 children. It is also one of the most serious allergies, capable of causing fatal and near-fatal reactions. Sensitive children can react not only… Read »

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