14
Oct
2019
Tag: CRISPR
8
Oct
2018
Bionest
Gene Therapy Update Part 1: Big Advances and Big Questions for CRISPR
The gene therapy field has seen several developments in recent months, especially around CRISPR, with both significant achievements and further controversies about the safety of the gene editing approach. CRISPR Cure for Duchenne’s Muscular Dystrophy (DMD) in Dogs Eric Olson’s team of researchers at the University of Texas Southwestern’s Harmon Center for Regenerative...
31
Jul
2017
Bionest
Human Germline Gene Editing Becomes Reality — at Least at the Research Stage
Back in April of this year, we wrote about the National Academies of Science and Medicine cautiously endorsing the possible use of gene editing at the germline level to correct serious diseases or medical conditions. Their report commented that scientists would likely be in a position to accomplish such activities safely within 5 to 10...
12
Jul
2017
Bionest
CRISPR Reaches the Clinic
Sometime mid-month, the first clinical trial employing CRISPR gene editing technology within the human body will initiate in China, at Sun-Yat Sen University. Scientists there will seek to use CRISPR and TALEN, another gene editing method, to treat persistent HPV infection and disable the tumor growth mechanism in infected cells. In a non-invasive approach, scientists...
8
May
2017
Bionest
A Look at Duchenne Muscular Dystrophy: Part 2 – About DMD, and Approaches to Treatment, Old and New
Duchenne Muscular Dystrophy (DMD) is a rare genetic disease characterized by progressive muscle degeneration and weakness. It is one of the most frequent genetic disorders, affecting approximately 1 of 3,600 (primarily) male children. The disease is caused by a mutation in the gene for dystrophin on the X chromosome that results in the absence of...
5
Oct
2016