CRISPR/Cas9 was first successfully demonstrated as a tool for genome editing in human cells in 2013. Since then, several advances have enabled the use of this technology to shut down a faulty gene, change a single DNA letter in a gene sequence, or add a new gene to an existing genome sequence. This summer has...
Last week we wrote about recent news in the field of CRISPR/Cas9 research. But CRISPR is not the only approach to gene editing under development, nor the most advanced. First Human Gene Editing Data — But Not from CRISPR Sangamo Therapeutics, Inc. has been developing an approach to gene editing based on zinc...
The gene therapy field has seen several developments in recent months, especially around CRISPR, with both significant achievements and further controversies about the safety of the gene editing approach. CRISPR Cure for Duchenne’s Muscular Dystrophy (DMD) in Dogs Eric Olson’s team of researchers at the University of Texas Southwestern’s Harmon Center for Regenerative...
Back in April of this year, we wrote about the National Academies of Science and Medicine cautiously endorsing the possible use of gene editing at the germline level to correct serious diseases or medical conditions. Their report commented that scientists would likely be in a position to accomplish such activities safely within 5 to 10...
Sometime mid-month, the first clinical trial employing CRISPR gene editing technology within the human body will initiate in China, at Sun-Yat Sen University. Scientists there will seek to use CRISPR and TALEN, another gene editing method, to treat persistent HPV infection and disable the tumor growth mechanism in infected cells. In a non-invasive approach, scientists...