The original vision of “personalized medicine” focused on tailoring medications to the biology of the individual patient — treating them with the right drug at the right time. That view has since evolved beyond therapy selection to increasingly encompass aspects of drug discovery, planning and delivery of care, and patient engagement. This new approach, now...
Considerable progress has been made in the fight against HIV/AIDS since the first cases of the disease in the 1980s. Today, successful antiretroviral drug regimens are able to reduce viral loads to undetectable levels, cutting the risk of transmission almost to zero and effectively transforming AIDS into a chronic disease in many developed countries. However,...
Virtual reality, the simulation of an environment that a user can interact with, and augmented reality, the superimposition of computer-generated images and sounds onto the real world, have gained the widespread use in video games and 3-D movies. But surprisingly, these technologies have found a growing number of diverse applications in medicine as well. ...
Depression is a challenging condition to treat. Most antidepressants take four to six weeks to take effect, and patient response to such drugs varies widely from person to person. As a result, most patients must try several drugs over a period of months before they can find relief. In March, the U.S. Food and Drug...
Few people like injections, which can limit adherence to therapy and even cause some patients to avoid potentially beneficial treatments altogether. As a result, drug developers have commonly viewed oral delivery as the “gold standard” for many therapies, especially for common chronic conditions. Formulating protein therapeutics for efficient delivery in a pill or capsule, however,...
Digital technologies are becoming an increasingly important part of modern healthcare. Medical devices have the ability to connect to and communicate with other devices or systems. Not only are new types of devices being created, but many existing devices are being updated with digital capabilities. As a result, the U.S. Food and Drug Administration (FDA)...
Immuno-oncology agents, particularly checkpoint inhibitors, have moved to the forefront of cancer research and treatment in recent years. Indeed, the discovery that cancer could be treated by activating the immune system was honored with a Nobel Prize in 2018. But, as revolutionary as immuno-oncology drugs have been for the cancer field, many patients still do...
Scientific evidence increasingly points to brain inflammation as a major driver of Alzheimer’s disease (AD). Researchers have discovered that amyloid, one of the hallmarks of the disease, is antimicrobial and may help the immune system fight invaders to the brain. They theorize that accumulating amyloid plaques and tau tangles in response to infection set the...
Wearables – including consumer products like FitBit wristbands and smartwatches – are quickly moving beyond their use as wellness products that track steps and sleep patterns to incorporate serious medical device capabilities and clinical applications. In September 2018, the Apple Series 4 model smartwatch became the first such product to have its software officially...
A recent survey published in the Journal of the American Medical Association (JAMA) reported that the medical marketing spend in the United States rose from approximately $17.7 billion in 1997 to just under $30 billion in 2016. The biggest growth came from Direct-to-Consumer (DTC) marketing, which increased from 11.9% to 32% of the total spend....